Multimodal management of pediatric carotid body tumors: a systematic review and case illustrations

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In Brief

The authors conducted a review of carotid body tumors, an extremely rare condition.

ABBREVIATIONS BTO = balloon test occlusion; CBT = carotid body tumor; CN = cranial nerve; ECA = external carotid artery; ICA = internal carotid artery; MIBG = iodine-123-meta-iodobenzylguanidine; PRISMA = Preferred Reporting Items for Systematic Reviews and Meta-Analyses.

Article Information

Correspondence Toba N. Niazi: University of Miami, Miami, FL. toba.niazi@mch.com.

INCLUDE WHEN CITING Published online December 7, 2018; DOI: 10.3171/2018.8.PEDS18393.

Disclosures The authors report no conflict of interest concerning the materials or methods used in this study or the findings specified in this paper.

© AANS, except where prohibited by US copyright law.

Headings

Figures

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    PRISMA flow diagram. Figure is available in color online only.

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    An 8-year-old girl with a neck mass. Sagittal (A) and coronal (B) MR images demonstrating a 3.4-cm contrast-enhancing lesion at the carotid bifurcation. Lateral (C) and anterior (D) views of right common carotid artery cerebral angiograms demonstrating arterial blush within lesion with ECA and ICA feeders. BTO of the right ICA (E) demonstrating adequate filling of right ICA. Postoperative coronal MR image (F) demonstrating gross-total resection of cervical lesion.

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    Immunohistochemistry on formalin-fixed, paraffin-embedded tissue was used for diagnosis. Type 1 chief cells stain positively for synaptophysin, which confirms the neuroendocrine origin and supports the diagnosis of paraganglioma. Figure is available in color online only.

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    Treatment paradigm for CBT management. CTA = CT angiography; MRA = MR angiography; VA = vertebral artery.

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