Intraventricular chordoid meningioma in a child: fever of unknown origin, clinical course, and response to treatment

Case report

Restricted access

The authors present the case of an 11-year-old boy with an intraventricular chordoid meningioma, which is a rare presentation of prolonged fever of unknown origin due to a rare tumor in a rare location. The fever resolved after excision of the lesion. Subsequent imaging revealed recurrence at 1 year. After a repeat excision and fractionated radiotherapy, the patient has remained disease free 5 years after the first surgery. Very few cases of intraventricular chordoid meningioma have been reported to date. The pathological features and clinical course are described. A review of the literature describing management options for this tumor type, recently found to have a higher recurrence rate, is described herein.

Abbreviations used in this paper:EMA = epithelial membrane antigen; FUO = fever of unknown origin.
Article Information

Contributor Notes

Address correspondence to: Ashok Pillai, M.D., D.N.B. (Neurosurgery), Department of Neurosurgery, Amrita College of Medicine, Elamakkara P.O., Edapally, Ernakulam, Kerala, India 682 026. email: include this information when citing this paper: published online October 12, 2012; DOI: 10.3171/2012.9.PEDS11398.

© AANS, except where prohibited by US copyright law.

  • 1

    Arima TNatsume AHatano HNakahara NFujita MIshii D: Intraventricular chordoid meningioma presenting with Castleman disease due to overproduction of interleukin-6. Case report. J Neurosurg 102:7337372005

    • Search Google Scholar
    • Export Citation
  • 2

    Caroli ERussillo MFerrante L: Intracranial meningiomas in children: report of 27 new cases and critical analysis of 440 cases reported in the literature. J Child Neurol 21:31362006

    • Search Google Scholar
    • Export Citation
  • 3

    Civit TBaylac FTaillandier LAuque JHepner H: [Chordoid meningiomas. Clinical, neuroradiological and anatomopathological aspects. Apropos of a new case and review of the literature.]. Neurochirurgie 43:3083131997. (Fr)

    • Search Google Scholar
    • Export Citation
  • 4

    Couce MEAker FVScheithauer BW: Chordoid meningioma: a clinicopathologic study of 42 cases. Am J Surg Pathol 24:8999052000

  • 5

    Denaro LDi Rocco FGessi MLauriola LLauretti LPallini R: Pyrogenic cytokine interleukin-6 expression by a chordoid meningioma in an adult with a systemic inflammatory syndrome. Case report and review of the literature. J Neurosurg 103:5555582005

    • Search Google Scholar
    • Export Citation
  • 6

    Donato GFerraro GSignorelli FIofrida GLavano AAmorosi A: Chordoid meningioma: case report and literature review. Ultrastruct Pathol 30:3093142006

    • Search Google Scholar
    • Export Citation
  • 7

    Kepes JJChen WYKConnors MHVogel FS: “Chordoid” meningeal tumors in young individuals with peritumoral lymphoplasmacellular infiltrates causing systemic manifestations of the Castleman syndrome. A report of 7 cases. Cancer 62:3914061988

    • Search Google Scholar
    • Export Citation
  • 8

    Kobata HKondo AIwasaki KKusaka HIto HSawada S: Chordoid meningioma in a child. Case report. J Neurosurg 88:3193231998

  • 9

    Modha AGutin PH: Diagnosis and treatment of atypical and anaplastic meningiomas: a review. Neurosurgery 57:5385502005

  • 10

    Moiyadi AVSridhar EGupta TRamadwar M: A primary optic nerve sheath chordoid meningioma. J Clin Neurosci 17:3973992010

  • 11

    Mullassery DO'Brien DFWilliams DCrooks DMallucci CPizer B: Malignant disseminated chordoid meningioma in a 12-year-old child: a role for early cranial and spinal radiation treatment after subtotal resection. Childs Nerv Syst 22:134413502006

    • Search Google Scholar
    • Export Citation
  • 12

    Sato TSugiyama TKawataki TSato E: Clear cell meningioma causing Castleman syndrome in a child. Case report. J Neurosurg Pediatr 5:6226252010

    • Search Google Scholar
    • Export Citation
  • 13

    Song KSPark SHCho BKWang KCPhi JHKim SK: Third ventricular chordoid meningioma in a child. Case report. J Neurosurg Pediatr 2:2692722008

    • Search Google Scholar
    • Export Citation
  • 14

    Szelényi J: Cytokines and the central nervous system. Brain Res Bull 54:3293382001

  • 15

    Yano HShinoda JHara AShimokawa KSakai N: Chordoid meningioma. Brain Tumor Pathol 17:1531572000



All Time Past Year Past 30 Days
Abstract Views 125 125 10
Full Text Views 54 52 1
PDF Downloads 155 148 1
EPUB Downloads 0 0 0
Google Scholar