Isolated pontine tuberculoma presenting as “fou rire prodromique”

Case report

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The authors present the case of a young child with “fou rire prodromique” as an initial manifestation of pontine tuberculoma. This report is the first description of fou rire prodromique as the presenting sign of CNS tuberculosis. The combination of clinical information and CT findings allowed for precise localization of the lesion and suggested tuberculoma as the possible etiology.

Article Information

Address correspondence to: Mohammed Azfar Siddiqui, M.D., Department of Radiodiagnosis, Jawaharlal Nehru Medical College, AMU, Aligarh-202002, India. email:

Please include this information when citing this paper: published online July 13, 2012; DOI: 10.3171/2012.5.PEDS12111.

© AANS, except where prohibited by US copyright law.



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    Noncontrast axial CT scan obtained at the level of the pons, showing a peripherally hyperdense lesion with surrounding perilesional edema causing expansion of the pons.

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    Contrast-enhanced axial CT scan revealing a conglomerated ring-enhancing lesion in the pons.

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    Follow-up axial CT scan obtained after 4 months of treatment with antitubercular medication, showing resolution of the pontine lesion.


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