The authors present a rare case of primary intracranial leiomyosarcoma (LMS) in a young, immunocompetent boy. The patient presented with an expanding right forehead mass. Diagnostic workup revealed multiple large intracranial tumors. The largest mass was resected, and pathological analysis revealed LMS. Given the poor prognosis of this tumor, the family declined further care, and the child died 3 months later. Primary LMSs are extremely rare tumors in the pediatric population, especially in patients who are not immunocompromised.
Abbreviations used in this paper:AFP = alpha-fetoprotein; β-hCG = β human chorionic gonadotropin; CA125 = cancer antigen 125; CEA = carcinoembryonic antigen; EBV = Epstein-Barr virus; LMS = leiomyosarcoma.
Address correspondence to: Paul M. Arnold, M.D., Department of Neurosurgery, Mail Stop 3021, University of Kansas Medical Center, 3901 Rainbow Boulevard, Kansas City, Kansas 66160. email: firstname.lastname@example.org.Please include this information when citing this paper: published online June 29, 2012; DOI: 10.3171/2012.4.PEDS1216.