Intracranial hypotension syndrome: a comprehensive review

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Intracranial hypotension may have variable clinical presentations, but has a rather uniform component of postural headache among its symptomatology. Its symptoms are explainable given the effects of the hypotension and attempts within the craniospinal axis to maintain volume homeostasis in the face of cerebrospinal fluid leakage (Monro–Kellie hypothesis). The imaging corollaries of the consequences of intracranial hypotension are especially well depicted on magnetic resonance imaging studies.

Abbreviations used in this paper:ICH = intracranial hypotension; CSF = cerebrospinal fluid; CT = computerized tomography; LP = lumbar puncture; MR = magnetic resonance; RC = radioisotope cisternography.

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Address reprint requests to: Michael S. Tenner, M.D., Department of Radiology, New York Medical College, Valhalla, New York 10595. email:

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