Spinal instability and deformity due to neoplastic conditions

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In addition to tumor resection, a major goal of spine surgery involving tumors is the preservation or achievement of spinal stability. The criteria defining stability, originally developed for use in trauma, are not directly applicable in the setting of neoplasia. The authors discuss the most common patterns of tumor-related instability and deformity at all levels of the spinal column and review the surgical options for treatment.

Abbreviations used in this paper:BMD = bone mineral density; CT = computerized tomography; MR = magnetic resonance imaging; PMMA = polymethylmethacrylate; VB = vertebral body; VSI = vertebral strength index.

In addition to tumor resection, a major goal of spine surgery involving tumors is the preservation or achievement of spinal stability. The criteria defining stability, originally developed for use in trauma, are not directly applicable in the setting of neoplasia. The authors discuss the most common patterns of tumor-related instability and deformity at all levels of the spinal column and review the surgical options for treatment.

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Address reprint requests to: Ziya L. Gokaslan, M.D., Department of Neurosurgery, Johns Hopkins University, Meyer 7-109, 600 North Wolfe Street, Baltimore, Maryland 21287. email: zgokasl1@jhmi.edu.

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