Definition of the adult Chiari malformation: a brief historical overview

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With the widespread use of newer neuroimaging techniques and modalities, significant tonsillar herniation is being diagnosed in more than 0.5% of patients, some of whom are asymptomatic. This puts the definition of the adult Chiari malformation to the test. The author provides a historical review of the evolution of the definition of the adult Chiari malformation in the neurosurgery, radiology, and pathology literature.

Abbreviations used in this paper:CSF = cerebrospinal fluid; ICP = intracranial pressure; MR = magnetic resonance.

With the widespread use of newer neuroimaging techniques and modalities, significant tonsillar herniation is being diagnosed in more than 0.5% of patients, some of whom are asymptomatic. This puts the definition of the adult Chiari malformation to the test. The author provides a historical review of the evolution of the definition of the adult Chiari malformation in the neurosurgery, radiology, and pathology literature.

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Address reprint requests to: Ghassan K. Bejjani, M.D., 200 Lothrop Street, Suite 5C, Pittsburgh, Pennsylvania 15213. email: bejjanigk@msx.upmc.edu.

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