Kazutoshi Yokoyama, Yoshitaka Asano, Takatsugu Murakawa, Mitsuaki Takada, Takashi Ando, Noboru Sakai, Hiromu Yamada and Hitoshi Iwata
✓ Brain arteriovenous malformations are considered to originate from a congenital maldevelopment of the brain vessels. Although there have been occasional reports suggesting a familial incidence of these lesions, data for only 10 families have been accumulated in the literature. The authors report on six such cases in three families. This high rate of occurrence of familial cases suggests an involvement of genetic factors.