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Frontal intradiploic encephalocele in a 44-year-old male patient: illustrative case

Baran Atli, Sebastian Rath, Johannes Burtscher, Johannes A. Hainfellner, and Simon Hametner


Encephaloceles are protrusions of the cerebral tissue through a skull defect. They occur mostly in children and very rarely in adults.


The authors present a case of a 44-year-old man presenting with a first-time generalized seizure. Computed tomography of the head showed bone destruction associated with a right frontal lesion. Magnetic resonance imaging scans demonstrated a largely isointense lesion in the intradiploic space that contained small, hyperintense nodular components and showed a low to moderate contrast agent enhancement.


The patient underwent resection, during which the histological examination found the lesion to be an intradiploic encephalocele. The patient had an uneventful postoperative course with a cessation of seizures. The imaging and neuropathological findings as well as a literature review, together with a discussion on the etiology of intradiploic encephaloceles, are contained in this report.