Browse

You are looking at 1 - 1 of 1 items for

  • Refine by Access: all x
  • By Author: Fleming, J. F. Ross x
  • By Author: Kondziolka, Douglas x
  • By Author: Bernstein, Mark x
Clear All
Restricted access

Douglas Kondziolka, Mark Bernstein, Lothar Resch, Charles H. Tator, J. F. Ross Fleming, R. G. Vanderlinden, and Hart Schutz

✓ A retrospective clinical and pathological review of 905 consecutive brain tumor cases (excluding pituitary adenoma and recurrent tumor) was conducted to identify cases in which intratumoral hemorrhage was confirmed grossly and/or pathologically. There were 132 cases so identified, for an overall tumor hemorrhage rate of 14.6%; of these, 5.4% were classified as macroscopic and 9.2% as microscopic. The presence of hemorrhage was correlated with the neurological presentation. The highest hemorrhage rate (70.0%) was found in patients with prior neurological history who experienced apoplectic deterioration (acute-on-chronic presentation). Only 57.1% of patients with acute deterioration in the absence of prior neurological symptoms had hemorrhages. The highest hemorrhage rate for primary brain tumors was 29.2% for mixed oligodendroglioma/astrocytoma, while the highest hemorrhage rate for any tumor type was 50% for metastatic melanoma. The clinical relevance of tumor hemorrhage is discussed.