Dandy’s hemispherectomies: historical vignette

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  • Department of Neurological Surgery, Loyola University Medical Center, Maywood, Illinois
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To better understand Walter Dandy’s intentions and the historical context of his work on hemispherectomy, the authors reviewed his original 1928 publication. Gliomas were considered incurable at that time. Presuming that the loss of motor function denoted a lack of useful tissue in that hemisphere, he pioneered radical removal of the involved cerebral hemisphere. Of the 5 patients operated on by Dandy, 1 died within 48 hours of hemorrhage because of a displaced vascular clip; 1 died of pneumonia in 2 weeks; 2 died of tumor recurrence, at 3 months and 3.5 years, respectively; and a fifth patient was lost to follow-up beyond the 2nd postoperative week.

The authors queried the Thomson Reuters Web of Science and Scopus. A total of 88 papers fulfilled inclusion criteria. Half of these papers (44/88) were published after 2012. Only 11% of papers (10/88) quoted Dandy’s paper accurately; half of them were published before 1997. Most publications (76% [67/88]) quoted Dandy incorrectly, all of them from 1997 and later. In the remaining 11 papers (13%), the accuracy of the quotes was unclear. The authors found a trend toward more accurate citation in earlier papers.

Critically reviewing Dandy’s report, with an understanding of the historical context, allows a better understanding of his intentions and the value of his contribution.

ABBREVIATIONS

MCA = middle cerebral artery.

Supplementary Materials

    • Supplemental Table 1 (PDF 549 KB)

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Contributor Notes

Correspondence G. Alexander Jones: Department of Neurological Surgery, Northwestern University Feinberg School of Medicine, Chicago, IL. alexander.jones@nm.org.

ACCOMPANYING EDITORIAL DOI: 10.3171/2020.11.JNS203624.

INCLUDE WHEN CITING Published online May 14, 2021; DOI: 10.3171/2020.9.JNS202824.

Disclosures The authors report no conflict of interest concerning the materials or methods used in this study or the findings specified in this paper.

  • 1

    Ostrom QT, Gittleman H, Truitt G, et al. CBTRUS Statistical Report: primary brain and other central nervous system tumors diagnosed in the United States in 2011–2015. Neuro Oncol. 2018;20(suppl 4):iv1iv86.

    • Search Google Scholar
    • Export Citation
  • 2

    Siegel RL, Miller KD, Jemal A. Cancer statistics, 2020. CA Cancer J Clin. 2020;70(1):730.

  • 3

    Louis DN, Perry A, Reifenberger G, et al. The 2016 World Health Organization Classification of Tumors of the Central Nervous System: a summary. Acta Neuropathol. 2016;131(6):803820.

    • Search Google Scholar
    • Export Citation
  • 4

    Molinaro AM, Taylor JW, Wiencke JK, Wrensch MR. Genetic and molecular epidemiology of adult diffuse glioma. Nat Rev Neurol. 2019;15(7):405417.

    • Search Google Scholar
    • Export Citation
  • 5

    Galicich JH, French LA, Melby JC. Use of dexamethasone in treatment of cerebral edema associated with brain tumors. J Lancet. 1961;81:4653.

    • Search Google Scholar
    • Export Citation
  • 6

    Walker MD, Alexander E Jr, Hunt WE, et al. Evaluation of BCNU and/or radiotherapy in the treatment of anaplastic gliomas. A cooperative clinical trial. J Neurosurg. 1978;49(3):333343.

    • Search Google Scholar
    • Export Citation
  • 7

    Westphal M, Hilt DC, Bortey E, et al. A phase 3 trial of local chemotherapy with biodegradable carmustine (BCNU) wafers (Gliadel wafers) in patients with primary malignant glioma. Neuro Oncol. 2003;5(2):7988.

    • Search Google Scholar
    • Export Citation
  • 8

    Stupp R, Mason WP, van den Bent MJ, et al. Radiotherapy plus concomitant and adjuvant temozolomide for glioblastoma. N Engl J Med. 2005;352(10):987996.

    • Search Google Scholar
    • Export Citation
  • 9

    Stupp R, Taillibert S, Kanner A, et al. Effect of tumor-treating fields plus maintenance temozolomide vs maintenance temozolomide alone on survival in patients with glioblastoma: a randomized clinical trial. JAMA. 2017;318(23):23062316.

    • Search Google Scholar
    • Export Citation
  • 10

    Stupp R, Mason WP, Van Den Bent MJ, et al. Concomitant and adjuvant temozolomide (TMZ) and radiotherapy (RT) for newly diagnosed glioblastoma multiforme (GBM). Conclusive results of a randomized phase III trial by the EORTC. Brain & RT Groups and NCIC Clinical Trials Group. J Clin Oncol. 2004;22 (14)(suppl):2.

    • Search Google Scholar
    • Export Citation
  • 11

    Bailey P, Cushing H. A Classification of the Tumors of the Glioma Group on a Histogenetic Basis with a Correlated Study of Prognosis. JB Lippincott; 1926.

    • Search Google Scholar
    • Export Citation
  • 12

    Bailey OT. Genesis of the Percival Bailey-Cushing classification of gliomas. Pediatr Neurosci. 1985-1986;12(4-5):261265.

  • 13

    Schulder M, Loeffler JS, Howes AE, et al. Historical vignette: The radium bomb: Harvey Cushing and the interstitial irradiation of gliomas. J Neurosurg. 1996;84(3):530532.

    • Search Google Scholar
    • Export Citation
  • 14

    Dandy WE. Special tumors of the brain. Glioma. In: Lewis D, ed. Practice of Surgery. Vol 12. WF Prior Co; 1932:510.

  • 15

    Dandy WE. Removal of right cerebral hemisphere for certain tumors with hemiplegia: preliminary report. J Am Med Assoc. 1928;90(11):823825.

    • Search Google Scholar
    • Export Citation
  • 16

    Beier AD, Rutka JT. Hemispherectomy: historical review and recent technical advances. Neurosurg Focus. 2013;34(6):E11.

  • 17

    Cushing H. Electrosurgery as an aid to the removal of intracranial tumors. Surg Gynecol Obstet. 1928;47:751784.

  • 18

    Malis LI. Electrosurgery. Technical note. J Neurosurg. 1996;85(5):970975.

  • 19

    Dandy WE. Brain tumors resections. In: Lewis D, ed. Practice of Surgery. Vol 12. WF Prior Co; 1932:492493.

  • 20

    Gardner WJ, Karnosh LJ, McClure CC Jr, Gardner AK. Residual function following hemispherectomy for tumour and for infantile hemiplegia. Brain. 1955;78(4):487502.

    • Search Google Scholar
    • Export Citation
  • 21

    Noetzel H. Diffusion von Blutfarbstoff in der inneren Randzone und äußeren Oberfläche des Zentralnervensystems bei subarachnoidaler Blutung. Arch Psychiatr Nervenkr. 1940;111(1):129138.

    • Search Google Scholar
    • Export Citation
  • 22

    Rasmussen T. Postoperative superficial hemosiderosis of the brain, its diagnosis, treatment and prevention. Trans Am Neurol Assoc. 1973;98:133137.

    • Search Google Scholar
    • Export Citation
  • 23

    Rasmussen T. Hemispherectomy for seizures revisited. Can J Neurol Sci. 1983;10(2):7178.

  • 24

    Dandy WE. Ventriculography following the injection of air into the cerebral ventricles. Ann Surg. 1918;68(1):511.

  • 25

    Beiko J, Suki D, Hess KR, et al. IDH1 mutant malignant astrocytomas are more amenable to surgical resection and have a survival benefit associated with maximal surgical resection. Neuro Oncol. 2014;16(1):8191.

    • Search Google Scholar
    • Export Citation
  • 26

    Skjulsvik AJ, HK, Jakola AS, et al. Is the anatomical distribution of low-grade gliomas linked to regions of gliogenesis? J Neurooncol. 2020;147(1):147157.

    • Search Google Scholar
    • Export Citation
  • 27

    Moher D, Liberati A, Tetzlaff J, Altman DG. Preferred reporting items for systematic reviews and meta-analyses: the PRISMA statement. PLoS Med. 2009;6(7):e1000097.

    • Search Google Scholar
    • Export Citation
  • 28

    Bassegoda Nonell J, García Gabarró G. La cátedra de Antoni Gaudí: estudio analítico de su obra. Universitat Politecnica de Catalunya; 1998.

    • Search Google Scholar
    • Export Citation

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