Deep brain stimulation (DBS) is a well-established therapy for patients with advanced Parkinson’s disease (PD), dystonia, and other movement disorders. In contrast to the strong positive effects that have been documented for motor symptoms, the effects of DBS on nonmotor symptoms have not been fully elucidated. Some reports suggest that stimulation of the subthalamic nucleus may improve lower urinary tract symptoms in patients with PD; however, reports of the effects of globus pallidus internus (GPi) DBS on urinary symptoms are limited. The authors present the case of a 49-year-old woman with PD who developed severe urinary incontinence after 27 months of GPi DBS. The urinary incontinence disappeared when stimulation was turned off, and reemerged after it was turned on again. After activation of a more dorsal contact in the left electrode, the patient’s urinary dynamics returned to normal.
MockS, OsbornDJ, BrownET, Stuart ReynoldsW, TurchanM, PallavaramS, : The impact of pallidal and subthalamic deep brain stimulation on urologic function in Parkinson’s disease. 19:717–723, 201610.1111/ner.1244627172446)| false
MordasiniL, KesslerTM, KissB, SchüpbachM, PolloC, Kaelin-LangA: Bladder function in patients with dystonia undergoing deep brain stimulation. 20:1015–1017, 201410.1016/j.parkreldis.2014.05.01624984838)| false
SakakibaraR, PanickerJ, Finazzi-AgroE, IacovelliV, BruschiniH: A guideline for the management of bladder dysfunction in Parkinson’s disease and other gait disorders. 35:551–563, 201610.1002/nau.2276425810035)| false