Gamma knife radiosurgery using 90 Gy for trigeminal neuralgia

Bradley Nicol M.D.1, William F. Regine M.D.1, Claire Courtney R.N., M.S.N.1, Ali Meigooni Ph.D.1, Michael Sanders M.S.1, and Byron Young M.D.1
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  • 1 Division of Neurosurgery and Department of Radiation Medicine, University of Kentucky, Lexington, Kentucky
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Object. The purpose of this paper was to assess the treatment of trigeminal neuralgia (TN) with the higher than normal dose of 90 Gy.

Methods. Forty-two patients with typical TN were treated over a 3-year period with gamma knife radiosurgery. Every patient received a maximum dose of 90 Gy in a single 4-mm isocenter targeted to the root entry zone of the trigeminal nerve. Thirty of 42 patients had undergone no prior treatments. The median follow-up period was 14 months (range 2–30 months).

Thirty-one patients (73.8%) achieved complete relief of pain. Nine patients (21.4%) obtained good pain control. Complications were limited to increased facial paresthesia in seven patients (16.7%) and dysgeusia in four patients (9.5%).

Conclusions. The authors conclude that the use of 90 Gy is a safe and effective dose for the treatment of TN.

JNS + Pediatrics - 1 year subscription bundle (Individuals Only)

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JNS + Pediatrics + Spine - 1 year subscription bundle (Individuals Only)

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