Electrothrombosis of saccular aneurysms via endovascular approach

Part 2: Preliminary clinical experience

Guido Guglielmi Department of Neurological Sciences, Therapeutic Neuroangiography, University of Rome Medical School, Rome, Italy; and Department of Radiological Sciences, Endovascular Therapy, University of California Medical Center, Los Angeles, California

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 M.D.
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Fernando Viñuela Department of Neurological Sciences, Therapeutic Neuroangiography, University of Rome Medical School, Rome, Italy; and Department of Radiological Sciences, Endovascular Therapy, University of California Medical Center, Los Angeles, California

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Jacques Dion Department of Neurological Sciences, Therapeutic Neuroangiography, University of Rome Medical School, Rome, Italy; and Department of Radiological Sciences, Endovascular Therapy, University of California Medical Center, Los Angeles, California

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 M.D.
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Gary Duckwiler Department of Neurological Sciences, Therapeutic Neuroangiography, University of Rome Medical School, Rome, Italy; and Department of Radiological Sciences, Endovascular Therapy, University of California Medical Center, Los Angeles, California

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Page Range:
8–14
Volume/Issue:
Volume 75: Issue 1
DOI link:
https://doi.org/10.3171/jns.1991.75.1.0008
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✓ Fifteen patients with high-risk intracranial saccular aneurysms were treated using electrolytically detachable coils introduced via an endovascular approach. The patients ranged in age from 21 to 69 years. The most frequent clinical presentation was subarachnoid hemorrhage (eight cases). Considerable thrombosis of the aneurysm (70% to 100%) was achieved in all 15 patients, and preservation of the parent artery was obtained in 14. Although temporary neurological deterioration due to the technique was recorded in one patient, no permanent neurological deficit was observed in this series and there were no deaths. It is believed that this new technology is a viable alternative in the management of patients with high-risk intracranial saccular aneurysms. It may also play an important role in the occlusion of aneurysms in the acute phase of subarachnoid hemorrhage.

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Contributor Notes

Address reprint requests to: Guido Guglielmi, M.D., Universita' di Roma, Dipartimento di Scienze Neurologiche, Neuroangiografia Terapeutica, Viale dell'Universita' 30/a, 00185 Roma, Italy.
  • 1.

    Guglielmi G, , Viñuela F, & Sepetka I, et al: Electrothrombosis of saccular aneurysms via endovascular approach. Part 1: Electrochemical basis, technique, and experimental results. J Neurosurg 75:1–7, 1991 Guglielmi G, Viñuela F, Sepetka I, et al: Electrothrombosis of saccular aneurysms via endovascular approach. Part 1: Electrochemical basis, technique, and experimental results. J Neurosurg 75:1–7, 1991

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  • 2.

    Hieshima GB, , Higashida RT, & Wapenski J, et al: Balloon embolization of a large distal basilar artery aneurysm. Case report. J Neurosurg 65:413–416, 1986 Hieshima GB, Higashida RT, Wapenski J, et al: Balloon embolization of a large distal basilar artery aneurysm. Case report. J Neurosurg 65:413–416, 1986

    • Search Google Scholar
    • Export Citation
  • 3.

    Higashida RT, , Halbach VV, & Barnwell SL, et al: Treatment of intracranial aneurysms with preservation of the parent vessel: results of percutaneous balloon embolization in 84 patients. AJNR 11:633–640, 1990 Higashida RT, Halbach VV, Barnwell SL, et al: Treatment of intracranial aneurysms with preservation of the parent vessel: results of percutaneous balloon embolization in 84 patients. AJNR 11:633–640, 1990

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    • Export Citation
  • 4.

    Hunt WE, & Hess RM: Surgical risk as related to time of intervention in the repair of intracranial aneurysms. J Neurosurg 28:14–20, 1968 Hunt WE, Hess RM: Surgical risk as related to time of intervention in the repair of intracranial aneurysms. J Neurosurg 28:14–20, 1968

    • Search Google Scholar
    • Export Citation
  • 5.

    Kassell NF, , Torner JC, & Haley EC Jr, et al: The International Cooperative Study on the Timing of Aneurysm Surgery. Part 1: Overall management results. J Neurosurg 73:18–36, 1990 Kassell NF, Torner JC, Haley EC Jr, et al: The International Cooperative Study on the Timing of Aneurysm Surgery. Part 1: Overall management results. J Neurosurg 73:18–36, 1990

    • Search Google Scholar
    • Export Citation
  • 6.

    Kassell NF, , Torner JC, & Jane JA, et al: The International Cooperative Study on the Timing of Aneurysm Surgery. Part 2: Surgical results. J Neurosurg 73:37–47, 1990 Kassell NF, Torner JC, Jane JA, et al: The International Cooperative Study on the Timing of Aneurysm Surgery. Part 2: Surgical results. J Neurosurg 73:37–47, 1990

    • Search Google Scholar
    • Export Citation
  • 7.

    Mullan S: Experiences with surgical thrombosis of intracranial berry aneurysms and carotid cavernous fistulas. J Neurosurg 41:657–670, 1974 Mullan S: Experiences with surgical thrombosis of intracranial berry aneurysms and carotid cavernous fistulas. J Neurosurg 41:657–670, 1974

    • Search Google Scholar
    • Export Citation
  • 8.

    Romodanov AP, & Shcheglov VI: Intravascular occlusion of saccular aneurysms of the cerebral arteries by means of a detachable balloon catheter. Adv Tech Stand Neurosurg 9:25–48, 1982 Romodanov AP, Shcheglov VI: Intravascular occlusion of saccular aneurysms of the cerebral arteries by means of a detachable balloon catheter. Adv Tech Stand Neurosurg 9:25–48, 1982

    • Search Google Scholar
    • Export Citation
  • 9.

    Weir B: Intracranial aneurysms and subarachnoid hemorrhage: an overview, in Wilkins RH, & Rengachary SS (eds): Neurosurgery. New York: McGraw-Hill, 1984, Vol 2, pp 1308–1329 Weir B: Intracranial aneurysms and subarachnoid hemorrhage: an overview, in Wilkins RH, Rengachary SS (eds): Neurosurgery. New York: McGraw-Hill, 1984, Vol 2, pp 1308–1329

    • Search Google Scholar
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