Giant gangliocytic paraganglioma of the filum terminale

Case report

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✓ The clinical and pathological features of a giant cauda equina paraganglioma arising from the intradural filum terminale is described. Scattered mature large neurons characterized the tumor as a gangliocytic paraganglioma. Histologically, these neoplasms have considerable similarity with ependymoma and the diagnosis can be easily missed unless special techniques are employed.

Article Information

Address for Dr. Baudrimont: Department of Pathology, Saint-Antoine Hospital, Paris, France.

Address reprint requests to: Michel Djindjian, M.D., Service de Neurochirurgie, Hôpital Henri Mondor, 94000 Créteil, France.

© AANS, except where prohibited by US copyright law.

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Figures

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    A: Photomicrograph of a semithin section stained by the silver technique of Rosenquist showing large neurons (single arrow) and paraganglionic cells (double arrow). × 100. B: Electron micrograph of the paraganglionic tumor cells showing dense-core vesicles, rough endoplasmic reticulum, and Golgi complex. × 5400. C: Electron micrograph showing cytoplasmic dense-core vesicles (arrows) in intermediate paraganglioma tumor cells. × 6300. D: Electron micrograph showing cytoplasmic dense-core vesicles in neuronal processes (arrows) containing mitochondria and neurofilaments. × 10,000.

References

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