Spontaneous resolution of multiple hemangiomas of the brain

Case report

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✓ A case of multiple intracerebral hemangiomas is reported. The lesions were angiographically hypervascular and accompanied by marked perifocal brain edema. After removal of the main lesion and postoperative steroid administration, the rest of the lesions resolved spontaneously. Histologically, the lesion was composed of capillaries and fibromyxoid stroma. The distinctive clinical, radiological and histological features of this lesion are discussed in contrast to several other types of intracranial vascular tumors.

Article Information

Address reprint requests to: Masamitsu Abe, M.D., D.Sc., Department of Neurosurgery, Saga Medical School, Saga 840-01, Japan.

© AANS, except where prohibited by US copyright law.

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Figures

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    Preoperative radiographic studies. Upper: Computerized tomography scans with contrast material administration demonstrating multiple nodular enhanced lesions with widespread areas of hypodensity in the bilateral frontoparietal lobes. Lower: Left carotid angiograms, arterial phase (left) and capillary phase (right), revealing a large nodular tumor stain (arrows) in the right frontal lobe and two smaller stains (arrowheads) in the left frontoparietal lobes.

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    Photomicrograph of the lesion showing an abundance of capillaries and fibromyxoid stroma. H & E, × 140.

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    Electron micrographs showing a capillary (C) and subendothelial cells. The subendothelial cells have abundant dilated cisterns of rough endoplasmic reticulum and occasional Weibel-Palade bodies (arrow). × 4000. Inset: Higher magnification of a Weibel-Palade body. × 40,000.

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