Diagnosis of an “isodense” pituitary microadenoma by dynamic CT scanning

Case report

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✓ A case of Nelson's syndrome with an adrenocorticotropic hormone-secreting pituitary chromophobe microadenoma is presented to demonstrate the potential capability of rapid sequential (dynamic) computerized tomography (CT) scanning for the diagnosis of a pituitary microadenoma that was isodense with the adjacent pituitary gland on conventional enhanced CT scanning. The dynamic CT scans showed transient high density in this microadenoma contrasting with the pituitary gland in the early-enhancement phase, and thereafter the contrast density was indistinguishable from that of the pituitary gland in the delayed-enhancement phase. For the detection of pituitary microadenoma, dynamic CT combined with subsequent delayed CT scanning can provide diagnostic and localizing information.

Article Information

Contributor Notes

Address reprint requests to: Takeshi Hasegawa, M.D., Department of Neurosurgery, School of Medicine, Kanazawa University, 13-1 Takaramachi, Kanazawa 920, Japan.

© AANS, except where prohibited by US copyright law.

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