Aminophylline plus nitroprusside and dopamine for treatment of cerebral vasospasm

A preliminary report

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✓ Cerebral vasospasm following subarachnoid hemorrhage continues to elude effective treatment. Volume expansion is very helpful at times, but cannot be relied on. The authors have combined elements of two vasospasm regimens that could have additive effects. After a trial of volume expansion, aminophylline, dopamine, and nitroprusside were used in combination in each of five patients. All had documented vasospasm and all improved markedly.

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Address reprint requests to: Walter J. Levy, M.D., N522, Neurosurgery, Division of Surgery, Medical Sciences Center, University of Missouri-Columbia, Columbia, Missouri 65212.
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