Cerebrospinal fluid shunt colonization and obstruction by Paecilomyces variotii

Case report

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✓ A 57-year-old woman underwent ventriculoperitoneal shunt placement for noncommunicating hydrocephalus. She required several shunt revisions over a 2-year period for recurrent hydrocephalus. The shunt was subsequently found to be obstructed by growth of the saprophytic fungus, Paecilomyces variotii, an infrequent human pathogen. Paecilomyces infections have caused complications associated with prosthetic cardiac valves and synthetic lens implantation; this is the first reported association with a cerebrospinal fluid shunt.

Article Information

Address reprint requests to: Byungse Suh, M.D., Ph.D., Section of Infectious Diseases, Temple University Health Sciences Center, Philadelphia, Pennsylvania 19140.

© AANS, except where prohibited by US copyright law.

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Figures

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    Septate hyphae of Paecilomyces variotii from centrifuged cerebrospinal fluid. Unstained, × 400.

  • View in gallery

    Mycelial plugs (arrows) in distal (a) and proximal (b) tips of the shunt. Unstained, × 1.75.

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