Localization in somatic sensory and motor areas of human cerebral cortex as determined by direct recording of evoked potentials and electrical stimulation

Clinton N. WoolseyDepartment of Neurophysiology and Waisman Center on Mental Retardation and Human Development, Division of Neurosurgery and Laboratory of Electroencephalography, University of Wisconsin-Madison Medical School, Madison, Wisconsin

Search for other papers by Clinton N. Woolsey in
Current site
Google Scholar
PubMed
Close
 M.D.
,
Theodore C. EricksonDepartment of Neurophysiology and Waisman Center on Mental Retardation and Human Development, Division of Neurosurgery and Laboratory of Electroencephalography, University of Wisconsin-Madison Medical School, Madison, Wisconsin

Search for other papers by Theodore C. Erickson in
Current site
Google Scholar
PubMed
Close
 M.D., Ph.D.
, and
Warren E. GilsonDepartment of Neurophysiology and Waisman Center on Mental Retardation and Human Development, Division of Neurosurgery and Laboratory of Electroencephalography, University of Wisconsin-Madison Medical School, Madison, Wisconsin

Search for other papers by Warren E. Gilson in
Current site
Google Scholar
PubMed
Close
 M.D.
Restricted access

Purchase Now

USD  $45.00

JNS + Pediatrics - 1 year subscription bundle (Individuals Only)

USD  $525.00

JNS + Pediatrics + Spine - 1 year subscription bundle (Individuals Only)

USD  $624.00
USD  $45.00
USD  $525.00
USD  $624.00
Print or Print + Online Sign in

✓ This paper reports and illustrates in figurine style results obtained by electrical stimulation of the cortex in 20 patients and by recording of cortical evoked potentials (EP's) in 13 of these patients, whose surgery required wide exposure of the Rolandic or paracentral regions of the cortex. This study is unique in that cutaneous receptive fields related to specific cortical sites were defined by mechanical stimulation, as is done in animals, in contrast to electrical stimulation of peripheral nerves at fixed sites, as in scalp EP recordings. Observations were made on pre- and postcentral gyri, on the second somatic sensory-motor area, on the supplementary motor area, and on the supplementary sensory area. In two patients with phantom limb pain, the pain was elicited in one on stimulation of the postcentral arm area, and in the other on stimulation of the supplementary sensory leg area. Surgical removal of these areas had the immediate effect of abolishing the phantoms and the pain. Long-term follow-up review was not possible. In one patient with severe Parkinson's disease, stimulating currents subthreshold for the elicitation of movement resulted in disappearance of tremor and rigidity for short periods after stimulation of the precentral gyrus. The possible patterns of organization of the human pre- and postcentral areas are considered and compared with those of the chimpanzee and other primates. In patients in whom data from pre- and postcentral gyri were adequate, it appeared that the precentral face-arm boundary is situated 1 to 2 cm higher than the corresponding postcentral boundary.

  • Collapse
  • Expand
  • 1.

    Adrian ED: Afferent discharges to the cerebral cortex from peripheral sense organs. J Physiol 100:159191, 1941 Adrian ED: Afferent discharges to the cerebral cortex from peripheral sense organs. J Physiol 100:159–191, 1941

    • Search Google Scholar
    • Export Citation
  • 2.

    Allison T, , Goff WR, & Williamson PD, et al: On the neural origin of early components of the human somatosensory evoked potential, in Desmedt JE (ed): Cerebral Evoked Potentials in Man. Basel: S Karger (In press, 1979) Allison T, Goff WR, Williamson PD, et al: On the neural origin of early components of the human somatosensory evoked potential, in Desmedt JE (ed): Cerebral Evoked Potentials in Man. Basel: S Karger (In press, 1979)

    • Search Google Scholar
    • Export Citation
  • 3.

    Bard P: Studies on the cortical representation of somatic sensibility. Bull NY Acad Med 14:585607, 1938 Bard P: Studies on the cortical representation of somatic sensibility. Bull NY Acad Med 14:585–607, 1938

    • Search Google Scholar
    • Export Citation
  • 4.

    Bates JAV: Stimulation of the medial surface of the human cerebral hemisphere after hemispherectomy. Brain 76:405447, 1953 Bates JAV: Stimulation of the medial surface of the human cerebral hemisphere after hemispherectomy. Brain 76:405–447, 1953

    • Search Google Scholar
    • Export Citation
  • 5.

    Blomquist AJ, & Ambrogi Lorenzini C: Projections of dorsal roots and sensory nerves to cortical sensory and motor regions of squirrel monkey. J Neurophysiol 28:11951205, 1965 Blomquist AJ, Ambrogi Lorenzini C: Projections of dorsal roots and sensory nerves to cortical sensory and motor regions of squirrel monkey. J Neurophysiol 28:1195–1205, 1965

    • Search Google Scholar
    • Export Citation
  • 6.

    Brickner RM: A human cortical area producing repetitive phenomena when stimulated. J Neurophysiol 3:128130, 1940 Brickner RM: A human cortical area producing repetitive phenomena when stimulated. J Neurophysiol 3:128–130, 1940

    • Search Google Scholar
    • Export Citation
  • 7.

    Brodmann K: Beitrage zur histologischen Lokalisation der Grosshirnrinde. VI. Mitteilung. Die Cortexgleiderung des Menschen. J Psychol Neurol 10:231246, 1908 Brodmann K: Beitrage zur histologischen Lokalisation der Grosshirnrinde. VI. Mitteilung. Die Cortexgleiderung des Menschen. J Psychol Neurol 10:231–246, 1908

    • Search Google Scholar
    • Export Citation
  • 8.

    Broughton RJ: Discussion of paper by Vaughan HG Jr, in Donchin E, & Lindsley DB (eds): Average Evoked Potentials. Methods, Results and Evaluation. Washington DC: NASA SP-191, pp 7984, 1969 Broughton RJ: Discussion of paper by Vaughan HG Jr, in Donchin E, Lindsley DB (eds): Average Evoked Potentials. Methods, Results and Evaluation. Washington DC: NASA SP-191, pp 79–84, 1969

    • Search Google Scholar
    • Export Citation
  • 9.

    Broughton RJ: Somatosensory Evoked Potentials in Man. McGill University (Ph.D. Thesis, 1967) Broughton RJ: Somatosensory Evoked Potentials in Man. McGill University (Ph.D. Thesis, 1967)

    • Search Google Scholar
    • Export Citation
  • 10.

    Campbell AW: Histological Studies on Localisation of Cerebral Function. Cambridge: Cambridge University Press, 1905, p 47 Campbell AW: Histological Studies on Localisation of Cerebral Function. Cambridge: Cambridge University Press, 1905, p 47

    • Search Google Scholar
    • Export Citation
  • 11.

    Celesia GG: Somatosensory evoked potentials recorded directly from human thalamus and Sm I cortical area. Arch Neurol 36:399405, 1979 Celesia GG: Somatosensory evoked potentials recorded directly from human thalamus and Sm I cortical area. Arch Neurol 36:399–405, 1979

    • Search Google Scholar
    • Export Citation
  • 12.

    Chang H-T: Dendritic potentials of cortical neurons produced by direct electrical stimulation of the cerebral cortex. J Neurophysiol 14:121, 1951 Chang H-T: Dendritic potentials of cortical neurons produced by direct electrical stimulation of the cerebral cortex. J Neurophysiol 14:1–21, 1951

    • Search Google Scholar
    • Export Citation
  • 13.

    Chusid JG, , de Gutiérrez-Mahoney CG, & Margules-Lavergne MP: Speech disturbances in association with parasagittal frontal lesions. J Neurosurg 11:193204, 1954 Chusid JG, de Gutiérrez-Mahoney CG, Margules-Lavergne MP: Speech disturbances in association with parasagittal frontal lesions. J Neurosurg 11:193–204, 1954

    • Search Google Scholar
    • Export Citation
  • 14.

    Dawson GD: Cerebral responses to electrical stimulation of peripheral nerve in man. J Neurol Neurosurg Psychiatry 10:134140, 1947 Dawson GD: Cerebral responses to electrical stimulation of peripheral nerve in man. J Neurol Neurosurg Psychiatry 10:134–140, 1947

    • Search Google Scholar
    • Export Citation
  • 15.

    Desmedt JE: Somatosensory cerebral evoked potentials in man, in Rémond A: Handbook of Electroencephalography and Clinical Neurophysiology. Amsterdam: Elsevier, 1971, Vol 9, pp 5582 Desmedt JE: Somatosensory cerebral evoked potentials in man, in Rémond A: Handbook of Electroencephalography and Clinical Neurophysiology. Amsterdam: Elsevier, 1971, Vol 9, pp 55–82

    • Search Google Scholar
    • Export Citation
  • 16.

    Dusser de Barenne JG, & McCulloch WS: An “extinction” phenomenon on stimulation of the cerebral cortex. Proc Soc Exp Biol Med 32:524527, 1934 Dusser de Barenne JG, McCulloch WS: An “extinction” phenomenon on stimulation of the cerebral cortex. Proc Soc Exp Biol Med 32:524–527, 1934

    • Search Google Scholar
    • Export Citation
  • 17.

    Erickson TC: Erotomania (nymphomania) as an expression of cortical epileptiform discharge. Arch Neurol Psychiatry 53:226231, 1945 Erickson TC: Erotomania (nymphomania) as an expression of cortical epileptiform discharge. Arch Neurol Psychiatry 53:226–231, 1945

    • Search Google Scholar
    • Export Citation
  • 18.

    Erickson TC, , Bleckwenn WJ, & Woolsey CN: Observations on the post central gyrus in relation to pain. Trans Am Neurol Assoc 77:5759, 1952 Erickson TC, Bleckwenn WJ, Woolsey CN: Observations on the post central gyrus in relation to pain. Trans Am Neurol Assoc 77:57–59, 1952

    • Search Google Scholar
    • Export Citation
  • 19.

    Erickson TC, & Woolsey CN: Observations on the supplementary motor area of man. Trans Am Neurol Assoc 76:5056, 1951 Erickson TC, Woolsey CN: Observations on the supplementary motor area of man. Trans Am Neurol Assoc 76:50–56, 1951

    • Search Google Scholar
    • Export Citation
  • 20.

    Ferrier D: The Croonian Lectures on Cerebral Localisation. London: Smith Elder and Co, 1890, p 29 Ferrier D: The Croonian Lectures on Cerebral Localisation. London: Smith Elder and Co, 1890, p 29

    • Search Google Scholar
    • Export Citation
  • 21.

    Foerster O: Motorische Felder und Bahnen, in Bumke O, & Foerster O (eds): Handbuch der Neurologie. Berlin: Springer, 1936, Vol 6, pp 1357 Foerster O: Motorische Felder und Bahnen, in Bumke O, Foerster O (eds): Handbuch der Neurologie. Berlin: Springer, 1936, Vol 6, pp 1–357

    • Search Google Scholar
    • Export Citation
  • 22.

    Foerster O: Sensible corticale Felder, in Bumke O, & Foerster O (eds): Handbuch der Neurologie. Berlin: Springer, 1936, Vol 6, pp 358448 Foerster O: Sensible corticale Felder, in Bumke O, Foerster O (eds): Handbuch der Neurologie. Berlin: Springer, 1936, Vol 6, pp 358–448

    • Search Google Scholar
    • Export Citation
  • 23.

    Forster FM, , Penfield W, & Jasper H, et al: Focal epilepsy, sensory precipitation and evoked cortical potentials. Electroencephalogr Clin Neurophysiol 1:349356, 1949 Forster FM, Penfield W, Jasper H, et al: Focal epilepsy, sensory precipitation and evoked cortical potentials. Electroencephalogr Clin Neurophysiol 1:349–356, 1949

    • Search Google Scholar
    • Export Citation
  • 24.

    Giblin DR: Somatosensory evoked potentials in healthy subjects and in patients with lesions of the nervous system. Ann NY Acad Sci 112:93142, 1964 Giblin DR: Somatosensory evoked potentials in healthy subjects and in patients with lesions of the nervous system. Ann NY Acad Sci 112:93–142, 1964

    • Search Google Scholar
    • Export Citation
  • 25.

    Goff WR, , Williamson PD, & VanGilder JC, et al: Neural origins of long latency evoked potentials recorded from the depth and cortical surface of the brain in man, in Desmedt JE (ed): Cerebral Evoked Potentials in Man. Basel: S Karger (In press, 1979) Goff WR, Williamson PD, VanGilder JC, et al: Neural origins of long latency evoked potentials recorded from the depth and cortical surface of the brain in man, in Desmedt JE (ed): Cerebral Evoked Potentials in Man. Basel: S Karger (In press, 1979)

    • Search Google Scholar
    • Export Citation
  • 26.

    Goldring S, , Jerva MJ, & Holmes TG, et al: Direct response of human cerebral cortex. Arch Neurol 4:590598, 1961 Goldring S, Jerva MJ, Holmes TG, et al: Direct response of human cerebral cortex. Arch Neurol 4:590–598, 1961

    • Search Google Scholar
    • Export Citation
  • 27.

    Goldring S, , Kelly DL Jr, & O'Leary JL: Somatosensory cortex of man as revealed by computer processing of peripherally evoked cortical potentials. Trans Am Neurol Assoc 89:108111, 1964 Goldring S, Kelly DL Jr, O'Leary JL: Somatosensory cortex of man as revealed by computer processing of peripherally evoked cortical potentials. Trans Am Neurol Assoc 89:108–111, 1964

    • Search Google Scholar
    • Export Citation
  • 28.

    Guidetti B: Désordres de la parole associés a des lésions de la surface interhémisphèrique frontal postérieure. Rev Neurol 97:121131, 1957 Guidetti B: Désordres de la parole associés a des lésions de la surface interhémisphèrique frontal postérieure. Rev Neurol 97:121–131, 1957

    • Search Google Scholar
    • Export Citation
  • 29.

    Hirsch JF, & Coxe WS: Representation of cutaneous tactile sensibility in cerebral cortex of Cebus. J Neurophysiol 21:481498, 1958 Hirsch JF, Coxe WS: Representation of cutaneous tactile sensibility in cerebral cortex of Cebus. J Neurophysiol 21:481–498, 1958

    • Search Google Scholar
    • Export Citation
  • 30.

    Hirsch JF, , Pertuiset B, & Calvet J, et al: Étude des réponses électrocorticales obtenues chez l'homme par des stimulations somesthésiques et visuelles. Electroencephalogr Clin Neurophysiol 13:411424, 1961 Hirsch JF, Pertuiset B, Calvet J, et al: Étude des réponses électrocorticales obtenues chez l'homme par des stimulations somesthésiques et visuelles. Electroencephalogr Clin Neurophysiol 13:411–424, 1961

    • Search Google Scholar
    • Export Citation
  • 31.

    Horsley V, & Schäfer EA: Experimental researches in cerebral physiology: I. On the functions of the marginal convolution. Proc R Soc Lond 36:437442, 1883–84 Horsley V, Schäfer EA: Experimental researches in cerebral physiology: I. On the functions of the marginal convolution. Proc R Soc Lond 36:437–442, 1883–84

    • Search Google Scholar
    • Export Citation
  • 32.

    Horsley V, & Schäfer EA: I. A record of experiments upon the functions of the cerebral cortex. Philos Trans R Soc Lond B 179:145, 1888 Horsley V, Schäfer EA: I. A record of experiments upon the functions of the cerebral cortex. Philos Trans R Soc Lond B 179:1–45, 1888

    • Search Google Scholar
    • Export Citation
  • 33.

    Jasper H, , Lende R, & Rasmussen T: Evoked potentials from the exposed somato-sensory cortex in man. J Nerv Ment Dis 130:526537, 1960 Jasper H, Lende R, Rasmussen T: Evoked potentials from the exposed somato-sensory cortex in man. J Nerv Ment Dis 130:526–537, 1960

    • Search Google Scholar
    • Export Citation
  • 34.

    Kelly DL Jr, , Goldring S, & O'Leary JL: Averaged evoked somatosensory responses from exposed cortex of man. Arch Neurol 13:19, 1965 Kelly DL Jr, Goldring S, O'Leary JL: Averaged evoked somatosensory responses from exposed cortex of man. Arch Neurol 13:1–9, 1965

    • Search Google Scholar
    • Export Citation
  • 35.

    Libet B: Electrical stimulation of cortex in human subjects and conscious sensory aspects, in Iggo A (ed): Somatosensory Systems, Handbook of Sensory Physiology. Berlin/Heidelberg/New York: Springer-Verlag, 1973, Vol 2, pp 743790 Libet B: Electrical stimulation of cortex in human subjects and conscious sensory aspects, in Iggo A (ed): Somatosensory Systems, Handbook of Sensory Physiology. Berlin/Heidelberg/New York: Springer-Verlag, 1973, Vol 2, pp 743–790

    • Search Google Scholar
    • Export Citation
  • 36.

    Libet B, , Alberts WW, & Wright FW Jr, et al: Cortical representation of evoked potentials relative to conscious sensory responses, and of somatic qualities in man, in Kornhuber HH (ed): The Somatosensory System. Stuttgart: Georg Thieme, 1975, pp 291308 Libet B, Alberts WW, Wright FW Jr, et al: Cortical representation of evoked potentials relative to conscious sensory responses, and of somatic qualities in man, in Kornhuber HH (ed): The Somatosensory System. Stuttgart: Georg Thieme, 1975, pp 291–308

    • Search Google Scholar
    • Export Citation
  • 37.

    Marshall C, & Walker AE: Electrocorticography. Bull Johns Hopkins Hosp 85:344359, 1949 Marshall C, Walker AE: Electrocorticography. Bull Johns Hopkins Hosp 85:344–359, 1949

    • Search Google Scholar
    • Export Citation
  • 38.

    Marshall WH, , Woolsey CN, & Bard P: Observations on cortical somatic sensory mechanisms of cat and monkey. J Neurophysiol 4:124, 1941 Marshall WH, Woolsey CN, Bard P: Observations on cortical somatic sensory mechanisms of cat and monkey. J Neurophysiol 4:1–24, 1941

    • Search Google Scholar
    • Export Citation
  • 39.

    Mills CK: Cerebral-localisation in its practical relations. Brain 12:233288; 358–406, 1889 Mills CK: Cerebral-localisation in its practical relations. Brain 12:233–288; 358–406, 1889

    • Search Google Scholar
    • Export Citation
  • 40.

    Murray EA, , Wise SP, & Coulter JD: The supplementary sensory area of the medial parietal cortex in the monkey. Personal communication, 1978 Murray EA, Wise SP, Coulter JD: The supplementary sensory area of the medial parietal cortex in the monkey. Personal communication, 1978

    • Search Google Scholar
    • Export Citation
  • 41.

    Pagni CA: Somato-sensory evoked potentials in thalamus and cortex of man. Electroencephalogr Clin Neurophysiol (Suppl 26):147155, 1967 Pagni CA: Somato-sensory evoked potentials in thalamus and cortex of man. Electroencephalogr Clin Neurophysiol (Suppl 26):147–155, 1967

    • Search Google Scholar
    • Export Citation
  • 42.

    Penfield W, & Boldrey E: Somatic motor and sensory representation in the cerebral cortex of man as studied by electrical stimulation. Brain 60:389443, 1937 Penfield W, Boldrey E: Somatic motor and sensory representation in the cerebral cortex of man as studied by electrical stimulation. Brain 60:389–443, 1937

    • Search Google Scholar
    • Export Citation
  • 43.

    Penfield W, & Jasper H: Epilepsy and the Functional Anatomy of the Human Brain. Boston: Little, Brown and Co, 1954, 896 pp Penfield W, Jasper H: Epilepsy and the Functional Anatomy of the Human Brain. Boston: Little, Brown and Co, 1954, 896 pp

    • Search Google Scholar
    • Export Citation
  • 44.

    Penfield W, & Rasmussen T: The Cerebral Cortex of Man. A Clinical Study of Localization of Function. New York: Macmillan, 1950, 248 pp Penfield W, Rasmussen T: The Cerebral Cortex of Man. A Clinical Study of Localization of Function. New York: Macmillan, 1950, 248 pp

    • Search Google Scholar
    • Export Citation
  • 45.

    Penfield W, & Roberts L: Speech and Brain-Mechanisms. Princeton: Princeton University Press, 1959 Penfield W, Roberts L: Speech and Brain-Mechanisms. Princeton: Princeton University Press, 1959

    • Search Google Scholar
    • Export Citation
  • 46.

    Penfield W, & Welch K: The supplementary motor area of the cerebral cortex. A clinical and experimental study. Arch Neurol Psychiatry 66:289317, 1951 Penfield W, Welch K: The supplementary motor area of the cerebral cortex. A clinical and experimental study. Arch Neurol Psychiatry 66:289–317, 1951

    • Search Google Scholar
    • Export Citation
  • 47.

    Purpura DP, & Grundfest H: Nature of dendritic potentials and synaptic mechanisms in cerebral cortex of cat. J Neurophysiol 19:573595, 1956 Purpura DP, Grundfest H: Nature of dendritic potentials and synaptic mechanisms in cerebral cortex of cat. J Neurophysiol 19:573–595, 1956

    • Search Google Scholar
    • Export Citation
  • 48.

    Richter CP, & Hines M: The production of the “grasp reflex” in adult macaques by experimental frontal lobe lesions. Res Publ Assoc Res Nerv Ment Dis 13:211224, 1932 Richter CP, Hines M: The production of the “grasp reflex” in adult macaques by experimental frontal lobe lesions. Res Publ Assoc Res Nerv Ment Dis 13:211–224, 1932

    • Search Google Scholar
    • Export Citation
  • 49.

    Scarff JE: Primary cortical centers for movements of upper and lower limbs in man. Observations based on electrical stimulation. Arch Neurol Psychiatry 44:243299, 1940 Scarff JE: Primary cortical centers for movements of upper and lower limbs in man. Observations based on electrical stimulation. Arch Neurol Psychiatry 44:243–299, 1940

    • Search Google Scholar
    • Export Citation
  • 50.

    Smith WK: The frontal eye fields, in Bucy PC (ed): The Precentral Motor Cortex. Urbana, Ill: University of Illinois Press, 1944, pp 307342 Smith WK: The frontal eye fields, in Bucy PC (ed): The Precentral Motor Cortex. Urbana, Ill: University of Illinois Press, 1944, pp 307–342

    • Search Google Scholar
    • Export Citation
  • 51.

    Stohr PE, & Goldring S: Origin of somatosensory evoked scalp responses in man. J Neurosurg 31:117127, 1969 Stohr PE, Goldring S: Origin of somatosensory evoked scalp responses in man. J Neurosurg 31:117–127, 1969

    • Search Google Scholar
    • Export Citation
  • 52.

    Sugar O, , Chusid JG, & French JD: A second motor cortex in the monkey (Macaca mulatta). J Neuropathol Exp Neurol 7:182189, 1948 Sugar O, Chusid JG, French JD: A second motor cortex in the monkey (Macaca mulatta). J Neuropathol Exp Neurol 7:182–189, 1948

    • Search Google Scholar
    • Export Citation
  • 53.

    Thompson JM, , Woolsey CN, & Talbot SA: Visual areas I and II of the cerebral cortex of rabbit. J Neurophysiol 13:277288, 1950 Thompson JM, Woolsey CN, Talbot SA: Visual areas I and II of the cerebral cortex of rabbit. J Neurophysiol 13:277–288, 1950

    • Search Google Scholar
    • Export Citation
  • 54.

    Travis AM: Neurological deficiencies following supplementary motor area lesions in Macaca mulatta. Brain 78:174198, 1955 Travis AM: Neurological deficiencies following supplementary motor area lesions in Macaca mulatta. Brain 78:174–198, 1955

    • Search Google Scholar
    • Export Citation
  • 55.

    Vogt C, & Vogt O: Allgemeinere Ergebnisse unserer Hirnforschung. J Psychol Neurol 25:279461, 1919–20 Vogt C, Vogt O: Allgemeinere Ergebnisse unserer Hirnforschung. J Psychol Neurol 25:279–461, 1919–20

    • Search Google Scholar
    • Export Citation
  • 56.

    Walker AE: Central representation of pain. Res Publ Assoc Res Nerv Ment Dis 23:6385, 1943 Walker AE: Central representation of pain. Res Publ Assoc Res Nerv Ment Dis 23:63–85, 1943

    • Search Google Scholar
    • Export Citation
  • 57.

    Welt C: Topographical Organization of Somatic Sensory and Motor Areas of the Cerebral Cortex of the Gibbon (Hylobates) and Chimpanzee (Pan). University of Wisconsin (Ph.D. Thesis, 1962) Welt C: Topographical Organization of Somatic Sensory and Motor Areas of the Cerebral Cortex of the Gibbon (Hylobates) and Chimpanzee (Pan). University of Wisconsin (Ph.D. Thesis, 1962)

    • Search Google Scholar
    • Export Citation
  • 58.

    Woolsey CN: Additional observations on a “second” somatic receiving area in the cerebral cortex of the monkey. Fed Proc 3:53, 1944 (Abstract) Woolsey CN: Additional observations on a “second” somatic receiving area in the cerebral cortex of the monkey. Fed Proc 3:53, 1944 (Abstract)

    • Search Google Scholar
    • Export Citation
  • 59.

    Woolsey CN: Comparative studies on cortical representation of vision. Vision Res 11 (Suppl 3):365382, 1971 Woolsey CN: Comparative studies on cortical representation of vision. Vision Res 11 (Suppl 3):365–382, 1971

    • Search Google Scholar
    • Export Citation
  • 60.

    Woolsey CN: Cortical localization as defined by evoked potential and electrical stimulation studies, in Schaltenbrand G, & Woolsey CN (eds): Cerebral Localization and Organization. Madison, Wis: University of Wisconsin Press, 1964, pp 1726 Woolsey CN: Cortical localization as defined by evoked potential and electrical stimulation studies, in Schaltenbrand G, Woolsey CN (eds): Cerebral Localization and Organization. Madison, Wis: University of Wisconsin Press, 1964, pp 17–26

    • Search Google Scholar
    • Export Citation
  • 61.

    Woolsey CN: Cortical motor map of Macaca mulatta after chronic section of the medullary pyramid, in Zülch KJ, , Creutzfeldt O, & Galbraith GC (eds): Cerebral Localization. Berlin/Heidelberg/New York: Springer-Verlag, 1975, pp 1731 Woolsey CN: Cortical motor map of Macaca mulatta after chronic section of the medullary pyramid, in Zülch KJ, Creutzfeldt O, Galbraith GC (eds): Cerebral Localization. Berlin/Heidelberg/New York: Springer-Verlag, 1975, pp 17–31

    • Search Google Scholar
    • Export Citation
  • 62.

    Woolsey CN: Organization of somatic sensory and motor areas of the cerebral cortex, in Harlow HF, & Woolsey CN (eds): Biological and Biochemical Bases of Behavior. Madison, Wis: University of Wisconsin Press, 1965, pp 6381 Woolsey CN: Organization of somatic sensory and motor areas of the cerebral cortex, in Harlow HF, Woolsey CN (eds): Biological and Biochemical Bases of Behavior. Madison, Wis: University of Wisconsin Press, 1965, pp 63–81

    • Search Google Scholar
    • Export Citation
  • 63.

    Woolsey CN, & Erickson TC: Study of the postcentral gyrus of man by the evoked potential technique. Trans Am Neurol Assoc 75:5052, 1950 Woolsey CN, Erickson TC: Study of the postcentral gyrus of man by the evoked potential technique. Trans Am Neurol Assoc 75:50–52, 1950

    • Search Google Scholar
    • Export Citation
  • 64.

    Woolsey CN, , Marshall WH, & Bard P: Representation of cutaneous tactile sensibility in the cerebral cortex of the monkey as indicated by evoked potentials. Bull Johns Hopkins Hosp 70:399441, 1942 Woolsey CN, Marshall WH, Bard P: Representation of cutaneous tactile sensibility in the cerebral cortex of the monkey as indicated by evoked potentials. Bull Johns Hopkins Hosp 70:399–441, 1942

    • Search Google Scholar
    • Export Citation
  • 65.

    Woolsey CN, , Settlage PH, & Meyer DR, et al: Patterns of localization in precentral and “supplementary” motor areas and their relation to the concept of a premotor area. Res Publ Assoc Res Nerv Ment Dis 30:238264, 1952 Woolsey CN, Settlage PH, Meyer DR, et al: Patterns of localization in precentral and “supplementary” motor areas and their relation to the concept of a premotor area. Res Publ Assoc Res Nerv Ment Dis 30:238–264, 1952

    • Search Google Scholar
    • Export Citation
  • 66.

    Woolsey CN, , Tasker R, & Welt C, et al: Organization of pre- and postcentral leg areas in chimpanzee and gibbon. Trans Am Neurol Assoc 85:144146, 1960 Woolsey CN, Tasker R, Welt C, et al: Organization of pre- and postcentral leg areas in chimpanzee and gibbon. Trans Am Neurol Assoc 85:144–146, 1960

    • Search Google Scholar
    • Export Citation
  • 67.

    Woolsey CN, , Walker AE, & Erickson TC: Somatic afferent representation in the cerebral cortex of man. IVe Congrès Neurologique International (Paris) 2:7071, 1949 Woolsey CN, Walker AE, Erickson TC: Somatic afferent representation in the cerebral cortex of man. IVe Congrès Neurologique International (Paris) 2:70–71, 1949

    • Search Google Scholar
    • Export Citation

Metrics

All Time Past Year Past 30 Days
Abstract Views 2041 378 63
Full Text Views 481 34 0
PDF Downloads 266 35 0
EPUB Downloads 0 0 0