Tolosa-Hunt syndrome: one cause of painful ophthalmoplegia

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✓ The author reports 12 cases of Tolosa-Hunt syndrome, a benign steroid-resistant cryptogenic granuloma that presents as painful ophthalmoplegia. This syndrome is differentiated from other causes of painful ophthalmoplegia including tumors, aneurysms, collagen disease, specific infections, mucoceles, and benign granulomas of unknown etiology. These other conditions should be excluded by appropriate tests. Surgical exploration is not necessary if there is a prompt remission on steroid therapy.

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Address reprint requests to: William E. Hunt, M.D., N-907 University Hospital, 410 West 10th Avenue, Columbus, Ohio 43210.
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References
  • 1.

    Berg EGay AJ: Tolosa-Hunt syndrome. Eye Ear Nose Throat Digest 29:51521967Berg E Gay AJ: Tolosa-Hunt syndrome. Eye Ear Nose Throat Digest 29:51–52 1967

    • Search Google Scholar
    • Export Citation
  • 2.

    Hallpike JF: Superior orbital fissure syndrome. Some clinical and radiological observations. J Neurol Neurosurg Psychiatry 36:4864901973Hallpike JF: Superior orbital fissure syndrome. Some clinical and radiological observations. J Neurol Neurosurg Psychiatry 36:486–490 1973

    • Search Google Scholar
    • Export Citation
  • 3.

    Hunt WEMeagher JNLeFever HEet al: Painful ophthalmoplegia. Its relation to indolent inflammation of the cavernous sinus. Neurology 11:56621961Hunt WE Meagher JN LeFever HE et al: Painful ophthalmoplegia. Its relation to indolent inflammation of the cavernous sinus. Neurology 11:56–62 1961

    • Search Google Scholar
    • Export Citation
  • 4.

    Jablonski S: Illustrated Dictionary of Eponymic Syndromes and Diseases and their Synonyms. Philadelphia/London/Toronto: WB Saunders1969 p 305Jablonski S: Illustrated Dictionary of Eponymic Syndromes and Diseases and their Synonyms. Philadelphia/London/Toronto: WB Saunders 1969 p 305

    • Search Google Scholar
    • Export Citation
  • 5.

    Lakke JPWF: Superior orbital fissure syndrome: report of a case caused by local pachymeningitis. Arch Neurol 7:2893001962Lakke JPWF: Superior orbital fissure syndrome: report of a case caused by local pachymeningitis. Arch Neurol 7:289–300 1962

    • Search Google Scholar
    • Export Citation
  • 6.

    Law WRNelson ER: Internal carotid aneurysm as a cause of Raeder's paratrigeminal syndrome. Neurology 18:43461968Law WR Nelson ER: Internal carotid aneurysm as a cause of Raeder's paratrigeminal syndrome. Neurology 18:43–46 1968

    • Search Google Scholar
    • Export Citation
  • 7.

    Mathew NTChandy J: Painful ophthalmoplegia. J Neurol Sci 11:2432561970Mathew NT Chandy J: Painful ophthalmoplegia. J Neurol Sci 11:243–256 1970

    • Search Google Scholar
    • Export Citation
  • 8.

    Milstein BAMorretin LB: Report of a case of sphenoid fissure syndrome studied by orbital venography. Am J Ophthalmol 72:6006031971Milstein BA Morretin LB: Report of a case of sphenoid fissure syndrome studied by orbital venography. Am J Ophthalmol 72:600–603 1971

    • Search Google Scholar
    • Export Citation
  • 9.

    Øther A: Painful ophthalmoplegia: report of a case. Acta Ophthalmol 45:3713731967Øther A: Painful ophthalmoplegia: report of a case. Acta Ophthalmol 45:371–373 1967

    • Search Google Scholar
    • Export Citation
  • 10.

    Raeder JG: “Paratrigeminal” paralysis of oculo-pupillary sympathetic. Brain 47:1491581924Raeder JG: “Paratrigeminal” paralysis of oculo-pupillary sympathetic. Brain 47:149–158 1924

    • Search Google Scholar
    • Export Citation
  • 11.

    Rochon-Duvigneau: Quelques cas de paralysie de tous les nerfs orbitaires (ophtalmoplégie totale avec amaurose et anesthésie dans la domaine de l'ophtalmique), d'origine syphilitique. Arch Ophtalmol (Paris) 16:7467601896Rochon-Duvigneau: Quelques cas de paralysie de tous les nerfs orbitaires (ophtalmoplégie totale avec amaurose et anesthésie dans la domaine de l'ophtalmique) d'origine syphilitique. Arch Ophtalmol (Paris) 16:746–760 1896

    • Search Google Scholar
    • Export Citation
  • 12.

    Schatz NJFarmer P: Tolosa-Hunt syndrome: the pathology of painful ophthalmoplegia in Smith JL (ed): Symposium of the University of Miami and the Bascom Palmer Eye Institute. Neuro-ophthalmology vol 6. St. Louis: CV Mosby1972 p 102Schatz NJ Farmer P: Tolosa-Hunt syndrome: the pathology of painful ophthalmoplegia in Smith JL (ed): Symposium of the University of Miami and the Bascom Palmer Eye Institute. Neuro-ophthalmology vol 6. St. Louis: CV Mosby 1972 p 102

    • Search Google Scholar
    • Export Citation
  • 13.

    Smith JLTaxdal DSR: Painful ophthalmoplegia: the Tolosa-Hunt syndrome. Am J Ophthalmol 61:146614721966Smith JL Taxdal DSR: Painful ophthalmoplegia: the Tolosa-Hunt syndrome. Am J Ophthalmol 61:1466–1472 1966

    • Search Google Scholar
    • Export Citation
  • 14.

    Sondheimer FKKnapp J: Angiographic findings in the Tolosa-Hunt syndrome: painful ophthalmoplegia. Radiology 106:1051121973Sondheimer FK Knapp J: Angiographic findings in the Tolosa-Hunt syndrome: painful ophthalmoplegia. Radiology 106:105–112 1973

    • Search Google Scholar
    • Export Citation
  • 15.

    Tolosa E: Periarteritic lesions of the carotid siphon with the clinical features of a carotid infraclinoidal aneurysm. J Neurol Neurosurg Psychiatry 17:300021954Tolosa E: Periarteritic lesions of the carotid siphon with the clinical features of a carotid infraclinoidal aneurysm. J Neurol Neurosurg Psychiatry 17:300–02 1954

    • Search Google Scholar
    • Export Citation
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