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In the summer of 1944 there became available for the first time a series of penetrating wounds of the brain due to shell fragments in which the patients had been treated with both sulfadiazine and systemically administered penicillin. This study (Table 1) is based on 50 such wounds, some of which had not been touched whereas others had received preliminary operations at forward hospitals.
There were 42 cases in which bacteriologic studies of the brain were made, either at operation or on admission to the hospital. The wounds were incurred from 3
EckerA. D.Tight dural closure with pedicled graft in wounds of the brain.J. Neurosurg.19452: 384–390.Ecker A. D. Tight dural closure with pedicled graft in wounds of the brain. J. Neurosurg. 1945 2: 384–390.