Long-term outcomes of wide-necked intracranial bifurcation aneurysms treated with T-stent–assisted coiling

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  • 1 Department of Neuroradiology, Istanbul University, Istanbul Medical Faculty, Capa;
  • 2 Department of Interventional Radiology, Koç University Hospital, Istanbul, Turkey;
  • 3 Department of Neuroradiology and Intracranial Endovascular Therapy, Alfried Krupp Krankenhaus, Essen, Germany; and
  • 4 Department of Neurosurgery, JSC Central Hospital, Almaty City, Kazakhstan
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OBJECTIVE

The endovascular treatment of complex bifurcation aneurysms possessing a neck that incorporates multiple side branches remains a surgical challenge. Double-stent–assisted coiling techniques, such as those with stents in an X and Y configuration, enable the endovascular treatment of wide-necked complex intracranial bifurcation aneurysms. However, the intraluminal struts at the intersection point in X- and Y-stents are not amenable to endothelialization, which may lead to thromboembolic complications. Stenting in the T configuration is a relatively new double-stent coiling technique. T-stenting differs from X- or Y-stenting in that there are no overlapping or intersecting stent segments. Promising short-term results of T-stent–assisted coiling were recently reported. However, the long-term results have not yet been demonstrated. This retrospective study investigated the long-term angiographic and clinical results in patients with wide-necked complex intracranial bifurcation aneurysms treated with T-stent–assisted coiling.

METHODS

A retrospective review was performed to identify patients with wide-necked complex intracranial bifurcation aneurysms treated with T-stent–assisted coiling at 4 institutions. The technical success and the initial and follow-up clinical and angiographic outcomes were assessed. Aneurysm filling status was assessed according to the Raymond classification. Periprocedural and delayed complications were reviewed. The neurological status of the patients was evaluated using the modified Rankin Scale (mRS).

RESULTS

One hundred two aneurysms in 102 patients (54 females), whose mean age was 57.9 ± 13.0 years, were included in the study. T-stenting was performed successfully in all patients. Immediate postprocedural angiography revealed complete occlusion in 83.3% of patients. Periprocedural complications developed in 13.7%, resulting in permanent morbidity in 1.9% and death in 1%. Eighty patients (78.4%) had at least one follow-up DSA examination performed at 6 months or later following the endovascular procedure. The mean duration of angiographic follow-up was 30.0 ± 16.3 months. The last follow-up examinations showed complete occlusion in 90.0% of patients. During the follow-up period, only 1 patient (1.3%) required retreatment. Delayed thromboembolic complications were observed in 4 patients (3.9%) without permanent morbidity. The mRS scores of all patients at the last clinical follow-up were between 0 and 2.

CONCLUSIONS

The short-term angiographic findings showed that T-stent–assisted coiling is a feasible and effective endovascular method to treat wide-necked complex bifurcation aneurysms. The long-term angiographic follow-up results suggest that T-stent–assisted coiling provides a durable treatment for wide-necked complex bifurcation aneurysms with favorable clinical outcomes, demonstrating the long-term safety of T-stent–assisted coiling.

ABBREVIATIONS ACoA = anterior communicating artery; MCA = middle cerebral artery; mRS = modified Rankin Scale; PCA = posterior cerebral artery; PCoA = posterior communicating artery; RC = Raymond class; SAH = subarachnoid hemorrhage.

Supplementary Materials

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Contributor Notes

Correspondence Kubilay Aydin: Istanbul University, Istanbul, Turkey. dr.aydink@gmail.com; dr.kubilay@me.com.

INCLUDE WHEN CITING Published online December 6, 2019; DOI: 10.3171/2019.9.JNS191733.

Disclosures The authors report no conflict of interest concerning the materials or methods used in this study or the findings specified in this paper.

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