A novel score to predict shunt dependency after aneurysmal subarachnoid hemorrhage

Restricted access

OBJECTIVE

Feasible clinical scores for predicting shunt-dependent hydrocephalus (SDHC) after aneurysmal subarachnoid hemorrhage (aSAH) are scarce. The chronic hydrocephalus ensuing from SAH score (CHESS) was introduced in 2015 and has a high predictive value for SDHC. Although this score is easy to calculate, several early clinical and radiological factors are required. The authors designed the retrospective analysis described here for external CHESS validation and determination of predictive values for the radiographic Barrow Neurological Institute (BNI) scoring system and a new simplified combined scoring system.

METHODS

Consecutive data of 314 patients with aSAH were retrospectively analyzed with respect to CHESS parameters and BNI score. A new score, the shunt dependency in aSAH (SDASH) score, was calculated from independent risk factors identified with multivariate analysis.

RESULTS

Two hundred twenty-five patients survived the initial phase after the hemorrhage, and 27.1% of these patients developed SDHC. The SDASH score was developed from results of multivariate analysis, which revealed acute hydrocephalus (aHP), a BNI score of ≥ 3, and a Hunt and Hess (HH) grade of ≥ 4 to be independent risk factors for SDHC (ORs 5.709 [aHP], 6.804 [BNI], and 4.122 [HH]; p < 0.001). All 3 SDHC scores tested (CHESS, BNI, and SDASH) reliably predicted chronic hydrocephalus (ORs 1.533 [CHESS], 2.021 [BNI], and 2.496 [SDASH]; p ≤ 0.001). Areas under the receiver operating curve (AUROC) for CHESS and SDASH were comparable (0.769 vs 0.785, respectively; p = 0.447), but the CHESS and SDASH scores were superior to the BNI grading system for predicting SDHC (BNI AUROC 0.649; p = 0.014 and 0.001, respectively). In contrast to CHESS and BNI scores, an increase in the SDASH score coincided with a monotonous increase in the risk of developing SDHC.

CONCLUSIONS

The newly developed SDASH score is a reliable tool for predicting SDHC. It contains fewer factors and is more intuitive than existing scores that were shown to predict SDHC. A prospective score evaluation is needed.

ABBREVIATIONS aHP = acute hydrocephalus; aSAH = aneurysmal SAH; AUROC = area under the receiver operating curve; BCI = bicaudate index; BNI = Barrow Neurological Institute; CHESS = chronic hydrocephalus ensuing from SAH score; FRI = failure risk index; ICH = intracerebral hemorrhage; IVH = intraventricular hemorrhage; SAH = subarachnoid hemorrhage; SDASH = shunt dependency in aSAH; SDHC = shunt-dependent hydrocephalus.

Article Information

Correspondence Nora F. Dengler, Department of Neurosurgery, Charité Universitätsmedizin Berlin, Augustenburger Platz 1, Berlin 13353, Germany. email: nora.dengler@charite.de.

INCLUDE WHEN CITING Published online June 9, 2017; DOI: 10.3171/2016.12.JNS162400.

Disclosures The authors report no conflict of interest concerning the materials or methods used in this study or the findings specified in this paper.

© AANS, except where prohibited by US copyright law.

Headings

Figures

  • View in gallery

    Development of SDHC in patients with aSAH according to different scores. A: CHESS. B: BNI. C: SDASH. ***p ≤ 0.001. D: AUROC.

References

TrendMD

Metrics

Metrics

All Time Past Year Past 30 Days
Abstract Views 215 215 41
Full Text Views 275 275 6
PDF Downloads 241 241 5
EPUB Downloads 0 0 0

PubMed

Google Scholar