Conception and design: Lonser, Heiss. Acquisition of data: Lonser, Heiss. Analysis and interpretation of data: Chittiboina. Drafting the article: Chittiboina. Critically revising the article: all authors. Reviewed submitted version of manuscript: all authors. Approved the final version of the manuscript on behalf of all authors: Lonser. Study supervision: Lonser, Heiss.