An Electrophysiological Study of Nerve Regeneration in the Cat

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Article Information

Work conducted under a fellowship granted by the National Foundation for Infantile Paralysis. Now of Western Reserve University School of Medicine, Cleveland, Ohio.

Now of Ohio State University School of Medicine, Columbus, Ohio.

© AANS, except where prohibited by US copyright law.

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Figures

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    Pairs of conducted nerve action potentials (A and C) and evoked responses of the posteroventral thalamic nucleus (B and D) at 20, 30, 90 and 120 days. Columns A and B, crushed interruption; columns C and D, cut and sutured. Comparisons indicate that for latency, duration and amplitude the crushed nerve action potentials were the more advanced for each stage. Compare lower amplitude, longer latency thalamic responses during early as compared with shorter latency, higher amplitude during later regeneration. White triangles indicate shock artifacts in thalamic records.

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    Plot of conduction velocity/regeneration time based upon average velocity across the neuroma. Note that for earlier regeneration intervals the curves for the crushed and for the cut and sutured nerves are nearly parallel, the crushed ones always showing more advanced regeneration. Similar curves were plotted for a 100 mm. conduction distance and for a 50 mm. stretch entirely below neuroma. These are not illustrated.

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    Plot of outside fiber diameter/regeneration time. Data approximate the characteristics of the conduction velocity curves of Fig. 2.

References

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