Editorial: Deep brain stimulation and aggression

Robert H. Howland Department of Psychiatry, University of Pittsburgh School of Medicine, Western Psychiatric Institute and Clinic, University of Pittsburgh Medical Center, Pittsburgh, Pennsylvania

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  • 1

    Anderson DJ: Optogenetics, sex, and violence in the brain: implications for psychiatry. Biol Psychiatry 71:10811089, 2012

  • 2

    Calogiuri G, , Weydahl A, & Carandente F: Methodological issues for studying the rest-activity cycle and sleep disturbances: a chronobiological approach using actigraphy data. Biol Res Nurs 15:512, 2013

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  • 3

    Didden R, , Sturmey P, , Sigafoos J, , Lang R, , O'Reilly MF, & Lancioni GE, Nature, prevalence, and characteristics of challenging behavior. Matson JL: Functional Assessment for Challenging Behaviors New York, Springer, 2012. 2544

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  • 4

    Fumagalli M, & Priori A: Functional and clinical neuroanatomy of morality. Brain 135:20062021, 2012

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    Gilbert F, , Vranic A, & Hurst S: Involuntary & voluntary invasive brain surgery: ethical issues related to acquired aggressiveness. Neuroethics 1:115128, 2013

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    Haller J: The neurobiology of abnormal manifestations of aggression—a review of hypothalamic mechanisms in cats, rodents, and humans. Brain Res Bull 93:97109, 2013

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  • 7

    Hariz MI, , Blomstedt P, & Zrinzo L: Deep brain stimulation between 1947 and 1987: the untold story. Neurosurg Focus 29:2 E1, 2010

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    Melanson EL, , Dykstra JC, & Szuminsky N: A novel approach for measuring energy expenditure in free-living humans. Conf Proc IEEE Eng Med Biol Soc 2009:68736877, 2009

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  • 9

    Torres CV, , Sola RG, , Pastor J, , Pedrosa M, , Navas M, & García-Navarrete E, et al.: Long-term results of posteromedial hypothalamic deep brain stimulation for patients with resistant aggressiveness. Clinical article. J Neurosurg [epub ahead of print June 7, 2013. DOI:10.3171/2013.4.JNS121639]

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  • 1

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  • 2

    Cooper SA, , Smiley E, , Jackson A, , Finlayson J, , Allan L, & Mantry D, et al.: Adults with intellectual disabilities: prevalence, incidence and remission of aggressive behaviour and related factors. J Intellect Disabil Res 53:217232, 2009

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  • 3

    Davison SE: The management of violence in general psychiatry. Adv Psychiatr Treat 11:362370, 2005

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    Emerson E, , Kiernan C, , Alborz A, , Reeves D, , Mason H, & Swarbrick R, et al.: Predicting the persistence of severe self-injurious behavior. Res Dev Disabil 22:6775, 2001

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  • 6

    Haller J, , Mikics E, , Halász J, & Tóth M: Mechanisms differentiating normal from abnormal aggression: glucocorticoids and serotonin. Eur J Pharmacol 526:89100, 2005

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  • 7

    Sano K, & Mayanagi Y: Posteromedial hypothalamotomy in the treatment of violent, aggressive behaviour. Acta Neurochir Suppl (Wien) 44:145151, 1988

  • 8

    Schermer M: Ethical issues in deep brain stimulation. Front Integr Neurosci 5:17, 2011

  • 9

    Siever LJ: Neurobiology of aggression and violence. Am J Psychiatry 165:429442, 2008

  • 10

    Totsika V, , Toogood S, , Hastings RP, & Lewis S: Persistence of challenging behaviours in adults with intellectual disability over a period of 11 years. J Intellect Disabil Res 52:446457, 2008

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