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The article by Elliott and colleagues4 in the Journal of Neurosurgery describes their experience with anterior temporal lobectomy for cases of pathologically proven mesial temporal sclerosis (MTS). The authors describe a retrospective analysis of their series of 116 consecutive patients with uniform pathology of MTS and fully concordant data of semiology, MRI findings, and electroencephalography (EEG). Their stated primary goal was to retrospectively identify predictors of long-term seizure outcome. The major finding was that “less disparity in the Wada memory scores between the ipsilateral and contralateral sides was associated with persistent seizures.”
Cohen-GadolAAWesterveldMAlvarez-CarillesJSpencerDD: Intracarotid Amytal memory test and hippocampal magnetic resonance imaging volumetry: validity of the Wada test as an indicator of hippocampal integrity among candidates for epilepsy surgery. J Neurosurg101:926–9312004
KanemotoKKawasakiJTakenouchiKHayashiKKuboHMorimuraT: Lateralized memory deficits on the Wada test correlate with the side of lobectomy only for patients with unilateral medial temporal lobe epilepsy. Seizure8:471–4751999