Editorial

Antibiotic-impregnated external ventricular drains

Restricted access

Most of us rely on CSF cultures to gauge our treatment of shunt infection. There is variation in the details of individual practice,1 but the decision that the antibiotics have done their job, and that it is safe to replace the shunt is usually based on CSF cultures from the external ventricular drain (EVD).

Six years ago, a randomized trial in adults demonstrated a reduced incidence of infection when antibiotic-impregnated (AI) EVDs were used.3 In that trial the intent was to prevent infection, not treat it. Known or suspected infections were specifically excluded. Since then, AI

Article Information

Please include this information when citing this paper: published online December 4, 2009; DOI: 10.3171/2009.10.JNS091123.

© AANS, except where prohibited by US copyright law.

Headings

References

1

Kestle JRGarton HJWhitehead WEDrake JMKulkarni AVCochrane DD: Management of shunt infections: a multicenter pilot study. J Neurosurg 105:3 Suppl1771812006

2

Stevens EAPalavecino ELSherertz RJShihabi ZKCouture DE: Effects of antibiotic-impregnated external ventricular drains on bacterial culture results: an in vitro analysis. Laboratory investigation. J Neurosurg Published online December 4 2009; DOI: 10.3171/2009.10.JNS09565

3

Zabramski JMWhiting DDarouiche ROHorner TGOlson JRobertson C: Efficacy of antimicrobial-impregnated external ventricular drain catheters: a prospective, randomized, controlled trial. J Neurosurg 98:7257302003

TrendMD

Metrics

Metrics

All Time Past Year Past 30 Days
Abstract Views 45 45 9
Full Text Views 74 74 3
PDF Downloads 34 34 1
EPUB Downloads 0 0 0

PubMed

Google Scholar