Rapid expansion of a previously asymptomatic subependymoma

Case report

Restricted access

✓ This 39-year-old man presented with a 6-month history of occipital headaches. Magnetic resonance imaging revealed an irregularly shaped fourth ventricle mass. One month after his initial presentation, he was admitted to the hospital with significant tumor expansion and clinical deterioration. A posterior fossa craniectomy was performed and the mass was resected. Histopathological analysis of this tumor showed central necrosis with associated edema in an otherwise typical and benign-appearing subependymoma. To the authors' knowledge, this is the first reported case of rapid, nonhemorrhagic expansion associated with necrosis in a previously asymptomatic subependymoma.

Article Information

Contributor Notes

Address reprint requests to: Mark Bernstein, M.D., Division of Neurosurgery, 399 Bathurst Street, Toronto Western Hospital, Toronto, Ontario M5T 2S8, Canada.
Headings
References
  • 1.

    Ecker RDPollock BE: Recurrent subependymoma treated with radiosurgery. Stereotact Funct Neurosurg 82:58602004Ecker RD Pollock BE: Recurrent subependymoma treated with radiosurgery. Stereotact Funct Neurosurg 82:58–60 2004

    • Search Google Scholar
    • Export Citation
  • 2.

    Hoeffel CBoukobza MPolivka MLot GGuichard JPLafitte Fet al: MR manifestations of subependymomas. AJNR Am J Neuroradiol 16:212121291995Hoeffel C Boukobza M Polivka M Lot G Guichard JP Lafitte F et al: MR manifestations of subependymomas. AJNR Am J Neuroradiol 16:2121–2129 1995

    • Search Google Scholar
    • Export Citation
  • 3.

    Im SHPack SHChoi YLChi JGKim DGJung HWet al: Clinicopathological study of seven cases of symptomatic supratentorial subependymoma. J Neurooncol 61:57672003Im SH Pack SH Choi YL Chi JG Kim DG Jung HW et al: Clinicopathological study of seven cases of symptomatic supratentorial subependymoma. J Neurooncol 61:57–67 2003

    • Search Google Scholar
    • Export Citation
  • 4.

    Kleihues PCavenee WK (eds): Pathology and Genetics of Tumours of the Nervous System. Lyon, France: IARC Press2000Kleihues P Cavenee WK (eds): Pathology and Genetics of Tumours of the Nervous System. Lyon France: IARC Press 2000

    • Search Google Scholar
    • Export Citation
  • 5.

    Maiuri FGangemi MIaconetta GSignorelli FDel Basso De Caro ML: Symptomatic subependymomas of the lateral ventricles. Report of eight cases. Clin Neurol Neurosurg 99:17221997Maiuri F Gangemi M Iaconetta G Signorelli F Del Basso De Caro ML: Symptomatic subependymomas of the lateral ventricles. Report of eight cases. Clin Neurol Neurosurg 99:17–22 1997

    • Search Google Scholar
    • Export Citation
  • 6.

    Ortiz-Reyes RDragovic LEriksson A: Sudden unexpected death resulting from previously nonsymptomatic subependymoma. Am J Forensic Med Pathol 23:63672002Ortiz-Reyes R Dragovic L Eriksson A: Sudden unexpected death resulting from previously nonsymptomatic subependymoma. Am J Forensic Med Pathol 23:63–67 2002

    • Search Google Scholar
    • Export Citation
  • 7.

    Prayson RASuh JH: Subependymomas: clinicopathologic study of 14 tumors, including comparative MIB-1 immunohistochemical analysis with other ependymal neoplasms. Arch Pathol Lab Med 123:3063091999Prayson RA Suh JH: Subependymomas: clinicopathologic study of 14 tumors including comparative MIB-1 immunohistochemical analysis with other ependymal neoplasms. Arch Pathol Lab Med 123:306–309 1999

    • Search Google Scholar
    • Export Citation
  • 8.

    Scheinker IM: Subependymoma: a newly recognized tumor of subependymal derivation. J Neurosurg 2:2322401945Scheinker IM: Subependymoma: a newly recognized tumor of subependymal derivation. J Neurosurg 2:232–240 1945

    • Search Google Scholar
    • Export Citation
  • 9.

    Scheithauer BW: Symptomatic subependymoma. Report of 21 cases and review of the literature. J Neurosurg 49:6896961978Scheithauer BW: Symptomatic subependymoma. Report of 21 cases and review of the literature. J Neurosurg 49:689–696 1978

    • Search Google Scholar
    • Export Citation
  • 10.

    Schiffer DChio AGiordana MTMigheli APalma LPollo Bet al: Histologic prognostic factors in ependymoma. Childs Nerv Syst 7:1771821991Schiffer D Chio A Giordana MT Migheli A Palma L Pollo B et al: Histologic prognostic factors in ependymoma. Childs Nerv Syst 7:177–182 1991

    • Search Google Scholar
    • Export Citation
  • 11.

    Seol HJHwang SKChoi YLChi JGJung HW: A case of recurrent subependymoma with subependymal seeding: case report. J Neurooncol 62:3153202003Seol HJ Hwang SK Choi YL Chi JG Jung HW: A case of recurrent subependymoma with subependymal seeding: case report. J Neurooncol 62:315–320 2003

    • Search Google Scholar
    • Export Citation
TrendMD
Metrics

Metrics

All Time Past Year Past 30 Days
Abstract Views 238 217 13
Full Text Views 62 34 0
PDF Downloads 136 31 0
EPUB Downloads 0 0 0
PubMed
Google Scholar