Authors:Zhuo Xi, Shane Burch, Praveen V. Mummaneni, Rory Richard Mayer, Charles Eichler and Dean Chou
The authors report the effect of obesitH5:H14+H5:H1410y on the oblique lumbar interbody fusion (OLIF) and perioperative morbidity in obese and nonobese patients. To their knowledge, there have been no reports on the effect of obesity on OLIF perioperative factors and morbidity.
The risk factors for postoperative medical complications in adult spinal deformity surgery were evaluated. The significant risks were a prognostic nutritional index < 50, male sex, and delayed ambulation. Improvement of preoperative nutritional status and postoperative early ambulation are important to avoid medical complications.
The authors investigated whether administration of zinc inhibits the growth of intracranial aneurysms (IAs) in a rat model. The results indicate that zinc administration may be a potent and useful therapy to prevent the enlargement and subsequent rupture of IAs. This study is important because the development of effective noninvasive medical therapies that reduce the risk of aneurysm growth and rupture is one of the most important challenges currently facing neurosurgeons.
Authors:Yasser B. Abulhasan, Johanna Ortiz Jimenez, Jeanne Teitelbaum, Gabrielle Simoneau and Mark R. Angle
In this retrospective cohort study, the authors analyzed outcomes of patients treated for vasospasm and identified risk factors associated with the development of refractory vasospasm. They showed that milrinone is safe at high doses when given intravenously (IV) or intraarterially (IA). Significant benefit was found with increasing IV and additional IA doses of milrinone, with favorable modified Rankin Scale scores, even when vasospasm was not reversed on imaging after rescue therapy. These findings shed light on the beneficial effect of milrinone, likely through multiple pathways.
Minimally invasive oblique interbody fusion for correction of iatrogenic lumbar deformity
Spinal instability may arise as a consequence of decompressive lumbar surgery. An oblique lumbar interbody fusion combined with pedicle screw fixation can provide indirect decompression on neural elements, stabilization of mobile spondylolisthesis, and restoration of segmental lordosis. Minimally invasive techniques may facilitate a shorter hospitalization and faster recovery than a traditional open revision operation. The authors describe the use of an anterior interbody fusion via an oblique retroperitoneal approach and posterior pedicle screw fixation to treat a 67-year-old woman who developed L3–4 and L4–5 unstable spondylolisthesis after a lumbar laminectomy.