Authors:Jordan I. Gewirtz, Alex Skidmore, Matthew D. Smyth, David D. Limbrick Jr., Manu Goyal, Joshua S. Shimony, Robert C. McKinstry, Mari L. Groves and Jennifer M. Strahle
The authors created an MRI spine protocol using fast sequencing to avoid sedation in pediatric patients and then assessed its use in identifying and monitoring syrinx and spinal dysraphism. They report the first pediatric series of a fast-sequence spine MRI protocol for use in young patients that does not require sedation and is able to identify and monitor syrinx and spinal dysraphism.
Authors:Ranjan Gupta, Justin P. Chan, Jennifer Uong, Winnie A. Palispis, David J. Wright, Sameer B. Shah, Samuel R. Ward, Thay Q. Lee and Oswald Steward
The study presents the first-ever description of the temporal profile of human motor endplate (MEP) degeneration following peripheral nerve injury (PNI) with the findings that MEP degeneration differs in time course between humans and mice or rodents and that denervated MEPs may persist in humans for years. The results highlight the importance of species-specific findings and may serve to objectively answer critical questions regarding the optimal timing of both surgical intervention and adjuvant treatments for PNIs.
Authors:Adham M. Khalafallah, Adrian E. Jimenez, Carlos G. Romo, David Olayinka Kamson, Lawrence Kleinberg, Jon Weingart, Henry Brem, Stuart A. Grossman and Debraj Mukherjee
The authors quantified the efficacy of multidisciplinary tumor boards (MDTBs) by tracking changes in diagnostic interpretations and treatment plans for brain tumor patients after their cases were discussed. The study results demonstrate that MDTB discussions led to a significant number of diagnostic and treatment plan changes, as well as shortened referral times, for patients whose cases were discussed, highlighting the clinical impact of multidisciplinary care within this patient population.
Authors:Nataly Raviv, Nicholas Field and Matthew A. Adamo
The authors evaluated postoperative pediatric neurosurgical patients in order to determine how common postoperative fevers are and how common and helpful workups are in these patients. The authors determined that performing invasive and costly fever workups are not worthwhile in these patients in the first 4 postoperative days.
Authors:Michael M. H. Yang, Jay Riva-Cambrin, Jonathan Cunningham, Nathalie Jetté, Tolulope T. Sajobi, Alex Soroceanu, Peter Lewkonia, W. Bradley Jacobs and Steven Casha
The authors developed a clinical prediction score to identify patients at risk of developing poor postoperative pain control after spine surgery. Seven variables predictive of inadequate pain control were incorporated into this score. This score accurately predicted the probability of heightened pain after elective spine surgery. The ability of clinicians to risk-stratify patients preoperatively creates an opportunity to develop anticipatory therapies and personalized clinical care pathways to improve pain outcomes after spine surgery.